Glycoimmunology
Lab
We are interested in elucidating the role of Glycosylation in immune response and cancer progression and in developing novel cell and antibody-based immunotherapy. Specifcally our research areas are the following:
We are interested in elucidating the role of Glycosylation in immune response and cancer progression and in developing novel cell and antibody-based immunotherapy. Specifcally our research areas are the following:
100+
Papers and book chapters published
4
Patents
10+
Years of Experience
The Glycoimmunology research lab employs unique molecular and biological methods combined with patient-centric approaches to disentangle biological mechanisms modulated by glycosylation and novel glycan-based therapies.
Our particular focus has been on sialylated glycans that affect the function of relevant cell surface molecules. We developed technologies to alter sialic acid contents and a multi-modular platform for high-throughput development of anti-glycan antibodies, with potential clinical application.
We collaborate extensively with pharmaceuticals and patient associations to translate into therapies for cancer and congenital disorders of glycosylation (CDG).
Elucidating the role of Glycosylation.